Identification of Hasegawa Dementia Scale‐Revised Cutoff Scores Associated With Mini‐Mental State Examination Thresholds for Anti‐Amyloid β Therapies in Patients With Amnesia
The identified HDS-R cutoff scores were associated with MMSE-defined cognitive thresholds and may serve as a potential reference for identifying patients who could be eligible for anti-Aβ therapies. The cognitive profile observed in Aβ-positive patients was characterised by deficits in delayed recall and in visual memory and by relatively preserved calculation ability, suggesting a selective vulnerability pattern in early Alzheimer's disease.
Authors
- Tomoyasu Matsubara (ORCID: https://orcid.org/0000-0002-7559-8284)
- Ryota Nakao
- Kazumi Nakamura
- Yuishin Izumi (ORCID: https://orcid.org/0000-0002-3048-9041)
- Masafumi Harada (ORCID: https://orcid.org/0000-0002-2345-9557)
- Koji Fujita (ORCID: https://orcid.org/0000-0003-4789-1579)
- Yoichi Otomi (ORCID: https://orcid.org/0000-0002-8960-3662)
- Yuki Yamamoto (ORCID: https://orcid.org/0000-0002-3385-338X)
- Kazuki Sogawa
- Shotaro Haji (ORCID: https://orcid.org/0000-0003-4768-0317)
- Kei Yamakami (ORCID: https://orcid.org/0009-0007-6448-1949)
- Kenta Hanada (ORCID: https://orcid.org/0009-0005-6905-5071)
- N. Kihara
Institutions
- Tokushima University (JP)
Publication Details
- Journal
- Psychogeriatrics
- Published
- 2025-10-26
- DOI
- https://doi.org/10.1111/psyg.70107
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Japan Society for the Promotion of Science