Drug repurposing of natural depsipeptide from Eleftheria terrae isolated via iChip for anti-breast cancer therapy
Diagram showing a drug development process using AI. Left panel depicts molecular structures of teixobactin and clovibactin. Middle section illustrates pharmacochemistry, ADMET pharmacokinetics, and pharmacodynamics targeting with clinical trial simulation using AI. Right section covers side effects, prognosis, and diagnosis using multimodal electronic health records.
Authors
- Abduh Riski (ORCID: https://orcid.org/0000-0003-2705-0641)
- Usama Ramadan Abdelmohsen (ORCID: https://orcid.org/0000-0002-1014-6922)
- Ma'sum Ma'sum
- Ahmed Mahal (ORCID: https://orcid.org/0000-0002-6977-3752)
- Nuriyatul Fhatonah
- La Ode Akbar Rasydy (ORCID: https://orcid.org/0000-0003-4774-654X)
- Nordin
- Tedi Rustandi
- Yomna Elghanam
- Imran Pashar
Institutions
- Universitas Gadjah Mada (ID)
- Guangdong Pharmaceutical University (CN)
- Regenex Pharmaceuticals (China) (CN)
- Universitas Muhammadiyah Tangerang (ID)
- Universitas Achmad Yani (ID)
- Lambung Mangkurat University (ID)
- Deraya University
- Chung-Ang University (KR)
- Minia University (EG)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fphar.2025.1694322
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00