Case Report: Long-term maintenance of GnRH-a combined with dienogest for thoracic endometriosis syndrome

Thoracic endometriosis syndrome is a rare form of endometriosis in which endometrial tissue is thought to migrate to the lungs and, with the onset of menstruation, the ectopic foci bleed, causing a range of pulmonary manifestations. In this paper we have collected the clinical data of two patients with thoracic endometriosis syndrome, both of whom presented with haemoptysis as the first symptom and had a history of endometriosis. After 6 courses of treatment with gonadotropin-releasing hormone analogues followed by maintenance treatment with dienogest, the patients' haemoptysis symptoms were relieved, the CT lesions in the lungs were significantly resorbed compared with the previous ones, and no recurrence was observed at long-term follow-up.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-10-27
DOI
https://doi.org/10.3389/fmed.2025.1670495
Citations
1
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
1.70
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article

Case Report: Long-term maintenance of GnRH-a combined with dienogest for thoracic endometriosis syndrome

Wanying Chen, Zheng Ma, Weiwei Wei, Jiming Chen et al.
1 citations
Frontiers in Medicine
Endometriosis Research and Treatment
1.70
article

Case Report: Long-term maintenance of GnRH-a combined with dienogest for thoracic endometriosis syndrome

Wanying Chen, Zheng Ma, Weiwei Wei, Jiming Chen, Qiucheng Jia, Huimin Tang
article en
1 citations

Abstract

Thoracic endometriosis syndrome is a rare form of endometriosis in which endometrial tissue is thought to migrate to the lungs and, with the onset of menstruation, the ectopic foci bleed, causing a range of pulmonary manifestations. In this paper we have collected the clinical data of two patients with thoracic endometriosis syndrome, both of whom presented with haemoptysis as the first symptom and had a history of endometriosis. After 6 courses of treatment with gonadotropin-releasing hormone analogues followed by maintenance treatment with dienogest, the patients' haemoptysis symptoms were relieved, the CT lesions in the lungs were significantly resorbed compared with the previous ones, and no recurrence was observed at long-term follow-up.

Frontiers in MedicineVol. 12
Nantong University (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Rugate Technologies (United States) (US), Changzhou No.2 People's Hospital (CN), Changzhou Third People's Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 12%
Endometriosis Research and Treatment
1.70
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