Ultrasound-responsive phase-transitional nanomedicine enables intensity-tunable postoperative analgesia
RDLP bridges imaging guidance and therapeutic intervention, leveraging ultrasound's deep tissue penetration and Rg3's natural biocompatibility to overcome limitations of conventional nerve blocks and ultrasound-responsive systems. This non-invasive, adjustable strategy offering potential to reduce opioid reliance and improve patient outcomes in perioperative care.
Authors
- Miao Feng (ORCID: https://orcid.org/0000-0003-4194-7236)
- Xinye Song (ORCID: https://orcid.org/0000-0002-8429-6886)
- Hao Chen (ORCID: https://orcid.org/0000-0003-4711-4438)
- Yong Luan
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fbioe.2025.1704679
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Sciences
- Natural Science Foundation of Liaoning Province
- Dalian Medical University
- Dalian Institute of Chemical Physics