Unraveling the genetic links between obesity or insulin resistance and breast cancer through the impact of CD295 and ITLN1 SNPs with DNA damage in a case-controlled study with bioinformatics analysis
CD295 (rs6700986) and ITLN1 (rs952804) SNPs should be considered as BC-associated susceptibility risk factors in obese, insulin resistance, or pre-diabetic individuals.
Authors
- Yasser O. Mosaad (ORCID: https://orcid.org/0000-0003-2566-5183)
- Queran Lin (ORCID: https://orcid.org/0000-0002-1757-9093)
- Ahmad A. Hady
- Nadia Μ. Hamdy (ORCID: https://orcid.org/0000-0003-2105-107X)
- Hekmat M. El Magdoub (ORCID: https://orcid.org/0000-0001-5742-6713)
- Doaa Fathi (ORCID: https://orcid.org/0000-0002-6412-7313)
- Razan Amjad
- Reham A.A. Elshimy (ORCID: https://orcid.org/0000-0002-1470-985X)
- Zayd Jastaniah
- Huda Altoukhi
- Hatim Z. Almarzouki (ORCID: https://orcid.org/0000-0002-4178-1320)
- Ahmed Abdelsamad
Institutions
- Ain Shams University (EG)
- Cairo University (EG)
- Witten/Herdecke University (DE)
- Mansoura University (EG)
- King Abdulaziz University (SA)
- Future University in Egypt (EG)
- Public Health England (GB)
- Knappschaftskrankenhaus Recklinghausen (DE)
- Faculty of Public Health (GB)
- King Abdulaziz Hospital (SA)
- Misr International University (EG)
- Alexandria University (EG)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fmed.2025.1703759
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00