PEDV and BVDV coinfection activates the NF-κB pathway by a TLR7-dependent mechanism
These results suggest that synergistic interactions between PEDV and BVDV during coinfection may strongly activate the host immune system and enhance virus replication. This study provides new insights into the immune modulation mechanisms underlying viral coinfections.
Authors
- Jie Tao (ORCID: https://orcid.org/0000-0002-3873-2413)
- Benqiang Li
- Huili Liu (ORCID: https://orcid.org/0000-0002-8841-2282)
- Ying Shi (ORCID: https://orcid.org/0000-0002-9263-4320)
- Jinghua Cheng (ORCID: https://orcid.org/0009-0006-6964-1211)
Institutions
- Shanghai Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fmicb.2025.1684847
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agricultural Science and Technology Innovation Program