Growth differentiation factor 11 modulates metabolism, mitigating the pro-tumoral behavior provided by M2-like macrophages in hepatocellular carcinoma-derived cells
This <i>in vitro</i> study suggests that mitigating tumor-promoting or M2-like macrophages with GDF11 may be an effective strategy for controlling the aggressiveness of HCC.
Authors
- Roxana U. Miranda-Labra (ORCID: https://orcid.org/0000-0001-8249-7257)
- Alejandro Escobedo‐Calvario (ORCID: https://orcid.org/0000-0002-8978-3122)
- Lisette Chávez-Rodríguez (ORCID: https://orcid.org/0000-0002-6678-0877)
- Rogélio Hernández‐Pando (ORCID: https://orcid.org/0000-0003-1292-3833)
- Araceli Páez (ORCID: https://orcid.org/0000-0003-4688-8271)
- Verónica Souza-Arroyo (ORCID: https://orcid.org/0000-0002-3923-6278)
- Leticia Bucio (ORCID: https://orcid.org/0000-0002-6963-2642)
- Luis E. Gómez-Quiroz (ORCID: https://orcid.org/0000-0002-5704-5985)
- Felipe Massó (ORCID: https://orcid.org/0000-0001-8671-3367)
- María Concepción Gutiérrez‐Ruíz (ORCID: https://orcid.org/0000-0003-0501-7226)
- Jens U. Marquardt (ORCID: https://orcid.org/0000-0002-8314-2682)
Institutions
- Universidad Autónoma de la Ciudad de México (MX)
- Universidad Autónoma Metropolitana (MX)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Technical University of Applied Sciences Lübeck (DE)
- Instituto Nacional de Cardiología (MX)
- University of Lübeck (DE)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3748/wjg.v31.i40.111307
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.59