Genetic mapping in collaborative cross mouse strains identifies loci that affect initial sensitivity to cocaine
Genetically defined and phenotypically divergent mouse strains are a useful tool for identifying candidate genes that influence behavioral responses to psychostimulants. Functional and mechanistic analyses of these genes could provide insights into biological processes that increase risk for CUD.
Authors
- Fernando Pardo‐Manuel de Villena (ORCID: https://orcid.org/0000-0002-5738-5795)
- Lisa M. Tarantino (ORCID: https://orcid.org/0000-0001-9984-2600)
- Martin T. Ferris (ORCID: https://orcid.org/0000-0003-1241-6268)
- Christiann H. Gaines
- Joseph Farrington (ORCID: https://orcid.org/0000-0003-4602-9741)
- William Valdar (ORCID: https://orcid.org/0000-0002-2419-0430)
- Jason A. Bubier (ORCID: https://orcid.org/0000-0001-5013-1234)
- Saad Khan (ORCID: https://orcid.org/0000-0002-7082-5230)
- Sarah A. Schoenrock (ORCID: https://orcid.org/0000-0001-7345-444X)
- Padam Kumar
Institutions
- University of North Carolina at Chapel Hill (US)
- Jackson Laboratory (US)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s00213-025-06901-z
- Primary Topic
- Genetic Mapping and Diversity in Plants and Animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health