An intraocular lens coated with polycaprolactone and methotrexate as a slow-release system for prophylaxis of posterior capsule opacification in-vitro
The proposed IOL showed favourable release kinetics and attenuated the main features of PCO formation, making it a prophylactic option with clinical potential.
Authors
- Arne J Speidel (ORCID: https://orcid.org/0000-0001-6005-1019)
- Simone C. Felis
- Armin Wolf (ORCID: https://orcid.org/0000-0002-6991-2214)
- Christian Wertheimer (ORCID: https://orcid.org/0000-0002-7017-7560)
- Anna Hillenmayer (ORCID: https://orcid.org/0000-0001-9433-3292)
- Christina Hilterhaus (ORCID: https://orcid.org/0009-0003-7187-0812)
Institutions
- Universität Ulm (DE)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1016/j.biopha.2025.118693
- Primary Topic
- Intraocular Surgery and Lenses
- Type
- article
- Field-Weighted Citation Impact
- 0.00