Decoding immune-metabolic crosstalk in ARDS: a transcriptomic exploration of biomarkers, cellular dynamics, and therapeutic pathways
SMARCD3 and TCN1 were identified as key biomarkers associated with immune cell and metabolic reprogramming in ARDS, while RPL14 was identified as a candidate biomarker through computational approaches, offering valuable insights for understanding the pathogenesis of the disease.
Authors
- Shuzhen Wei (ORCID: https://orcid.org/0000-0001-7804-1548)
- Min Wang (ORCID: https://orcid.org/0000-0002-2357-589X)
- Qin Wang (ORCID: https://orcid.org/0000-0002-5947-875X)
- Ming Ding (ORCID: https://orcid.org/0000-0002-6376-3174)
- Jing Huang (ORCID: https://orcid.org/0009-0002-7218-9845)
- Jingyuan Xu (ORCID: https://orcid.org/0000-0002-2153-8091)
- Wei Zhou (ORCID: https://orcid.org/0000-0002-3152-7898)
- Yuan Lu (ORCID: https://orcid.org/0000-0002-9103-5211)
- Ting Wu (ORCID: https://orcid.org/0000-0003-1691-984X)
Institutions
- Zhongda Hospital Southeast University (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Community Health Center (US)
- Jinling Institute of Technology (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fimmu.2025.1615748
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00