Initial experience of spatially fractionated lattice radiation therapy for palliative treatment of pediatric bulky tumors
SFRT seems to be a safe and effective palliative treatment for pediatric bulky tumor patients in our preliminary study. Radiobiologic modeling suggests that increasing the density of high-dose cores can enhance the therapeutic ratio, potentially reducing normal tissue toxicity.
Authors
- Arthur J. Olch (ORCID: https://orcid.org/0000-0002-0814-5891)
- Brittney Chau
- Hualin Zhang (ORCID: https://orcid.org/0000-0002-3972-0107)
- Eric Chang (ORCID: https://orcid.org/0000-0002-7496-1192)
- Kenneth K. Wong (ORCID: https://orcid.org/0000-0001-8560-9007)
- Hye Ri Han
- Lauren Lukas
Institutions
- University of Southern California (US)
- Children's Hospital of Los Angeles (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fonc.2025.1648847
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Southern California