Predictive model of sperm DNA fragmentation in infertile men based on lifestyle factors
A predictive model incorporating six modifiable lifestyle factors was developed and validated for assessing the risk of abnormal sperm DFI in infertile men. This nomogram provides a simple and clinically practical tool for early screening and individualized intervention to improve reproductive outcomes.
Authors
- Mengjia Pan
- Yan Xu (ORCID: https://orcid.org/0000-0001-5653-291X)
- Xin Huang (ORCID: https://orcid.org/0000-0001-5404-4437)
- Ningxin Qin
- Ke Wang (ORCID: https://orcid.org/0000-0002-5388-8643)
- You Zhang (ORCID: https://orcid.org/0000-0002-8033-2755)
- Wei Chen (ORCID: https://orcid.org/0000-0002-2139-1368)
- Ni Song (ORCID: https://orcid.org/0000-0003-2836-8440)
Institutions
- XinHua Hospital (CN)
- Sanda University (CN)
- Shanghai First Maternity and Infant Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fendo.2025.1675168
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China
- Tongji University