Phytochemical-rich Eucommia ulmoides leaf extract extends healthspan in Caenorhabditis elegans via the pmk-1/p38 MAPK pathway and mitochondrial homeostasis
These results provide robust evidence supporting the use of EUL as a natural dietary supplement to prolong healthspan, establishing a scientific rationale for its application in promoting healthy aging.
Authors
- Xingwen Xie (ORCID: https://orcid.org/0000-0002-7118-5431)
- Xiaofeng Shi
- Jiaojiao Li (ORCID: https://orcid.org/0009-0008-2549-1113)
- Jiaxu Zhang (ORCID: https://orcid.org/0000-0002-2177-1889)
- Quhuan Ma
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fnut.2025.1680518
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00