The diagnostic and prognostic value of CXCL13, CXCL10, and CXCL8 in patients with neurosyphilis
CSF-CXCL13 has good differential value in distinguishing NS from Non-NS, NS from CNS infections, while CSF-CXCL10 and CSF-CXCL8 have lower differential sensitivity. The diagnostic performance of the NS diagnostic model (Model 1) based on CSF-CXCL13 has been improved.
Authors
- Chen Zou (ORCID: https://orcid.org/0000-0002-1605-1449)
- Chen Chen (ORCID: https://orcid.org/0000-0002-0565-0841)
- Zihao Xia (ORCID: https://orcid.org/0000-0003-1310-7678)
- Qin Wang (ORCID: https://orcid.org/0000-0001-6514-5874)
- Rentian Cai (ORCID: https://orcid.org/0000-0003-0350-1276)
- Hongxia Wei (ORCID: https://orcid.org/0009-0008-2153-9132)
- Hongjing Guan
- Jingli Peng
- Xiaoyun Di
Institutions
- Nanjing University of Chinese Medicine (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fimmu.2025.1654251
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AIDS Healthcare Foundation
- Jiangsu Commission of Health