Novel insights and clinical perception of the patients with acute leukemia transferred to ICU: a multi-center retrospective study spanning 10 years
The prognosis and outcomes for AL patients transferred to the ICU were generally poor. Some molecular biological and cytogenetic indicators can be used as early warning indicators for AL patients' transfer to the ICU or short-term death. Acute respiratory failure, sepsis, and severe infections were the primary reasons for ICU admission. Heart failure, CRRT, and APACHE II score ≥20 were identified as independent risk factors for mortality, while vasopressor use was an independent risk factor for OS.
Authors
- Qicai Guo
- Minjuan Zeng (ORCID: https://orcid.org/0000-0002-3983-2352)
- Xiaojun Chen (ORCID: https://orcid.org/0000-0002-3698-2814)
- Jiachen Xie (ORCID: https://orcid.org/0009-0001-6336-670X)
- Yanquan Liu (ORCID: https://orcid.org/0000-0001-6826-0456)
- Zuohong Cao
- Jianzhen Shen
- Ye Li (ORCID: https://orcid.org/0000-0002-8647-384X)
- Zhichao Li (ORCID: https://orcid.org/0000-0002-5314-2112)
- Huidong Guo (ORCID: https://orcid.org/0009-0007-6914-4706)
- Yue Yin (ORCID: https://orcid.org/0009-0002-1884-3236)
Institutions
- Fujian Medical University (CN)
- Guangdong Medical College (CN)
- Ganzhou People's Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Union Hospital (CN)
- Putian University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fmed.2025.1657610
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Putian University
- Fujian Medical University
- Health Commission of Jiangxi Province
- Gannan Medical University