Case Report: Bilateral lens dislocation as an atypical presentation of acromegaly and review of the ocular effects of GH/IGF-1 excess
Bilateral lens dislocation may represent an atypical presentation of acromegaly. It may indicate advanced disease and, if confirmed in other cohorts, could be considered among the suggestive signs of acromegaly. In our case, the use of pasireotide allowed adherence to therapy and optimal therapeutic response in a multicomplicated, non-self-sufficient patient.
Authors
- Biagio Cangiano (ORCID: https://orcid.org/0000-0002-2658-744X)
- Stefano Frara (ORCID: https://orcid.org/0000-0002-1308-5598)
- Laura Vitale (ORCID: https://orcid.org/0000-0003-2831-1794)
- Letizia Maria Fatti (ORCID: https://orcid.org/0000-0002-1219-8953)
- Marco Bonomi (ORCID: https://orcid.org/0000-0001-5454-6074)
- Luca Persani (ORCID: https://orcid.org/0000-0003-2068-9581)
- Giovanni Vitale (ORCID: https://orcid.org/0000-0003-2478-683X)
Institutions
- University of Milan (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- Link Campus University (IT)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fendo.2025.1666425
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute