Prognostic modeling for diffuse midline glioma: development and validation of a risk stratification nomogram using SEER and institutional cohorts
This study presents the first large-scale, SEER-based nomogram for DMG, offering reliable prognostic stratification and reinforcing the survival benefit of combined chemoradiotherapy. The model's clinical utility is further supported by real-world institutional validation, underscoring its potential to inform individualized treatment strategies in DMG.
Authors
- Wanyue Han
- Huandi Zhou (ORCID: https://orcid.org/0000-0002-2617-6157)
- Xiaoying Xue (ORCID: https://orcid.org/0000-0002-4934-2904)
- Ge Zhang (ORCID: https://orcid.org/0000-0002-1663-8979)
- Lei Lou
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3389/fonc.2025.1644388
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00