A breast cancer patient developed γδ T-cell acute lymphoblastic leukemia after chemotherapy: a case report with literary review

Gamma delta T-cell (γδ T-cell) acute lymphoblastic leukemia(γδ T-ALL) is rare and aggressive, but secondary γδ T-ALL following breast cancer is more rare. Our case presents a patient with breast cancer, received surgical treatment and chemotherapy consisting of epirubicin and cyclophosphamide. Three years later, the patient got secondary γδ T-ALL. The chemotherapeutic agents had a significant effect on the breast cancer patient, who has an increased risk of secondary γδ T-ALL.

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Publication Details

Journal
Annals of Hematology
Published
2025-10-27
DOI
https://doi.org/10.1007/s00277-025-06690-7
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
0.00
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article

A breast cancer patient developed γδ T-cell acute lymphoblastic leukemia after chemotherapy: a case report with literary review

Xinhong Yang, Zhihua Zhang, Xiaofeng Yang, Xue Wu
Annals of Hematology
Acute Lymphoblastic Leukemia research
article

A breast cancer patient developed γδ T-cell acute lymphoblastic leukemia after chemotherapy: a case report with literary review

Xinhong Yang, Zhihua Zhang, Xiaofeng Yang, Xue Wu
article en

Abstract

Gamma delta T-cell (γδ T-cell) acute lymphoblastic leukemia(γδ T-ALL) is rare and aggressive, but secondary γδ T-ALL following breast cancer is more rare. Our case presents a patient with breast cancer, received surgical treatment and chemotherapy consisting of epirubicin and cyclophosphamide. Three years later, the patient got secondary γδ T-ALL. The chemotherapeutic agents had a significant effect on the breast cancer patient, who has an increased risk of secondary γδ T-ALL.

Annals of HematologyVol. 104(10)
Affiliated Hospital of Chengde Medical College (CN)
Openalex Percentile: Top 59%
Acute Lymphoblastic Leukemia research
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