A breast cancer patient developed γδ T-cell acute lymphoblastic leukemia after chemotherapy: a case report with literary review
Gamma delta T-cell (γδ T-cell) acute lymphoblastic leukemia(γδ T-ALL) is rare and aggressive, but secondary γδ T-ALL following breast cancer is more rare. Our case presents a patient with breast cancer, received surgical treatment and chemotherapy consisting of epirubicin and cyclophosphamide. Three years later, the patient got secondary γδ T-ALL. The chemotherapeutic agents had a significant effect on the breast cancer patient, who has an increased risk of secondary γδ T-ALL.
Authors
- Xinhong Yang
- Zhihua Zhang (ORCID: https://orcid.org/0009-0001-3542-2209)
- Xiaofeng Yang (ORCID: https://orcid.org/0000-0002-1707-1388)
- Xue Wu (ORCID: https://orcid.org/0000-0002-4800-8226)
Institutions
- Affiliated Hospital of Chengde Medical College (CN)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s00277-025-06690-7
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00