Intermittent MDMA Attenuates Ovariectomy-induced Bone Loss via a Gut Microbiota–Bone Axis
These findings suggest that intermittent MDMA may mitigate OVX-induced BMD loss in association with remodeling of a gut microbiota-bone axis. Future studies should define causal microbial and metabolic mediators and evaluate generalizability across additional bone-loss models.
Authors
- Rumi Murayama
- Akifumi Eguchi (ORCID: https://orcid.org/0000-0001-5858-8132)
- Kenji Hashimoto (ORCID: https://orcid.org/0000-0002-8892-0439)
- Chisato Mori (ORCID: https://orcid.org/0000-0002-1144-8316)
- Xiayun Wan (ORCID: https://orcid.org/0000-0002-5173-2071)
Institutions
- Chiba University (JP)
- Teikyo University Chiba Medical Center (JP)
- Center for Forensic Mental Health, Chiba University (JP)
Publication Details
- Journal
- Clinical Psychopharmacology and Neuroscience
- Published
- 2025-10-27
- DOI
- https://doi.org/10.9758/cpn.25.1309
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22