Genetic Variability and Prediction of T Epitopes of the HPV16 E2 Gene in Asymptomatic Women from Cajamarca, Peru

The A HPV16 lineage predominated among the women studied. The identified SNPs indicate substantial variability in the E2 gene and a relationship with endocervical lesions. In total, 29 E2-derived T-cell epitopes with immunogenic potential were identified.

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Publication Details

Journal
Viruses
Published
2025-10-25
DOI
https://doi.org/10.3390/v17111420
Primary Topic
vaccines and immunoinformatics approaches
Type
article
Field-Weighted Citation Impact
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article

Genetic Variability and Prediction of T Epitopes of the HPV16 E2 Gene in Asymptomatic Women from Cajamarca, Peru

Yordi Tarazona-Castro, Angela Cornejo‐Tapia, Lorena Becerra-Goicochea, Wilmer Silva-Caso et al.
Viruses
vaccines and immunoinformatics approaches
article

Genetic Variability and Prediction of T Epitopes of the HPV16 E2 Gene in Asymptomatic Women from Cajamarca, Peru

Yordi Tarazona-Castro, Angela Cornejo‐Tapia, Lorena Becerra-Goicochea, Wilmer Silva-Caso, Eliezer Bonifacio-Velez de Villa, Ronald Aquino-Ortega, Miguel Ángel Aguilar-Luis, Juana del Valle-Mendoza, Deysi Aguilar-Luis, Dayana Denegri-Hinostroza
article en

Abstract

The A HPV16 lineage predominated among the women studied. The identified SNPs indicate substantial variability in the E2 gene and a relationship with endocervical lesions. In total, 29 E2-derived T-cell epitopes with immunogenic potential were identified.

VirusesVol. 17(11)
Peruvian University of Applied Sciences (PE), National University of Cajamarca (PE)
Openalex Percentile: Top 73%
vaccines and immunoinformatics approaches
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