Stretched Radial Trajectory Design for Efficient MRI with Enhanced K-Space Coverage and Image Resolution
We present a stretched radial trajectory design that enhances image resolution in MRI by expanding k-space coverage without increasing readout duration or scan time. The method dynamically modulates gradient amplitudes as a function of projection angle, achieving square k-space coverage in 2D and cubic coverage in 3D imaging. Validation was conducted using phantom and in vivo experiments on GE and Siemens scanners at 0.55 T and 3 T. Point spread function analysis and reconstructed images demonstrated improved sharpness and clearer visualization of fine structures, including small phantom details and brain vasculature. The approach also increased T<sub>1</sub> and T<sub>2</sub> mapping accuracy in MRF acquisitions. The proposed strategy requires no additional scan time or gradient hardware capability, making it well-suited for MRI systems with moderate performance. It offers a simple and generalizable means to improve spatial resolution in both structural and quantitative imaging applications.
Authors
- Yanjun Qian (ORCID: https://orcid.org/0000-0002-1581-0431)
- Zhitao Li (ORCID: https://orcid.org/0000-0003-3462-6549)
- Congyu Liao (ORCID: https://orcid.org/0000-0003-2270-276X)
- Liang Gong (ORCID: https://orcid.org/0000-0003-0265-1192)
- Yang Yang (ORCID: https://orcid.org/0000-0002-2841-4243)
- Xiaozhi Cao (ORCID: https://orcid.org/0000-0001-5095-648X)
- Kawin Setsompop (ORCID: https://orcid.org/0000-0003-0455-7634)
- Qinghua Li (ORCID: https://orcid.org/0000-0001-5291-1445)
- Zihan Zhou (ORCID: https://orcid.org/0000-0002-9034-0951)
Institutions
- Northwestern University (US)
- University of California, San Francisco (US)
- University of California, Irvine (US)
- Stanford Medicine (US)
- Siemens Healthcare (United States) (US)
- Stanford University (US)
Publication Details
- Journal
- Bioengineering
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3390/bioengineering12111152
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00