Clinical Outcomes of Later‐Generation <scp>EGFR</scp> ‐ <scp>TKIs</scp> for Uncommon <scp>EGFR</scp> Mutations in <scp>NSCLC</scp> : A Multicenter Real‐World Study

Later-generation EGFR-TKIs were associated with improved outcomes in patients with uncommon EGFR mutations, with afatinib showing favorable treatment duration in G719X and compound subtypes.

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Publication Details

Journal
Thoracic Cancer
Published
2025-10-01
DOI
https://doi.org/10.1111/1759-7714.70179
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00

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Clinical Outcomes of Later‐Generation EGFR ‐ TKIs for Uncommon EGFR Mutations in NSCLC : A Multicenter Real‐World Study

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Clinical Outcomes of Later‐Generation EGFR ‐ TKIs for Uncommon EGFR Mutations in NSCLC : A Multicenter Real‐World Study

Kohei Horiuchi, Yoshitaka Oyamada, Kenzo Soejima, Shigenari Nukaga, Tetsuo Tani, Shinnosuke Ikemura, Keiko Ohgino, Fumio Sakamaki, Hideki Terai, Taro Shinozaki, Koichi Fukunaga, Lisa Shigematsu, Hiroyuki Yasuda, Katsuhiko Naoki, Takashi Sato, Koichi Sayama
article en

Abstract

Later-generation EGFR-TKIs were associated with improved outcomes in patients with uncommon EGFR mutations, with afatinib showing favorable treatment duration in G719X and compound subtypes.

Thoracic CancerVol. 16(20)
Keio University (JP), Tokai University Hachioji Hospital (JP), Tokyo Medical Center (JP), Kawasaki Municipal Hospital (JP), Tokyo National Hospital (JP), Kitasato University (JP), University of Yamanashi (JP), Icahn School of Medicine at Mount Sinai (US)
Keio University
Openalex Percentile: Top 55%
Lung Cancer Treatments and Mutations
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Clinical Outcomes of Later‐Generation <scp>EGFR</scp> ‐ <scp>TKIs</scp> for Uncommon <scp>EGFR</scp> Mutations in <scp>NSCLC</scp> : A Multicenter Real‐World Study — Kohei Horiuchi, Yoshitaka Oyamada, et al. · Thoracic Cancer (2025) | TGRS Research Map | TGRS