Identification of druggable targets in melanoma by multi-omics Mendelian randomization integrated with transcriptomic and spatial analysis
This study provides robust genetic and therapeutic evidence for targeting EPS15L1 and HGS in CM treatment.
Authors
- Jiahua Xing (ORCID: https://orcid.org/0000-0003-1805-7446)
- Muzi Chen (ORCID: https://orcid.org/0000-0003-2078-2014)
- Mingyong Yang
- Ran Tao (ORCID: https://orcid.org/0000-0002-6240-1411)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-10-26
- DOI
- https://doi.org/10.3389/fgene.2025.1657356
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00