Impact of Bovine Serum Albumin on the Antioxidant and Anti‐Inflammatory Activities of <i>Arbutus unedo</i> L. Extract
This study explored the impact of bovine serum albumin (BSA) on the antioxidant and anti‐inflammatory activities of Arbutus unedo leaf extract and its polyphenolic compounds. HPLC‐MS analysis identified compounds like quinic acid, arbutin, and flavonoids. Antioxidant activity was evaluated using ferric reducing power, phosphomolybdenum, and DPPH assays, while anti‐inflammatory effects were assessed via red blood cell membrane stability. BSA enhanced hydroxyl radical scavenging but reduced ferric reducing power and total antioxidant capacity, with no significant anti‐inflammatory improvement. The findings reveal assay‐dependent effects of BSA due to protein–polyphenol interactions, emphasizing the need for further research to optimize therapeutic potential.
Authors
- Natale Badalamenti (ORCID: https://orcid.org/0000-0001-7961-3894)
- Fehmi Boufahja (ORCID: https://orcid.org/0000-0001-8220-0396)
- Maurizio Bruno (ORCID: https://orcid.org/0000-0003-0583-0487)
- Idir Moualek (ORCID: https://orcid.org/0000-0002-4455-5556)
- Stefanıa Garzoli (ORCID: https://orcid.org/0000-0001-8535-0533)
- Karim Houalı (ORCID: https://orcid.org/0000-0002-7317-8657)
- Karima Benarab (ORCID: https://orcid.org/0009-0005-0539-5261)
- Hamdi Bendif (ORCID: https://orcid.org/0009-0009-5980-391X)
Institutions
- Imam Mohammad ibn Saud Islamic University (SA)
- Mouloud Mammeri University of Tizi-Ouzou (DZ)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Journal of Food Biochemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/jfbc/9947897
- Primary Topic
- Phytochemicals and Antioxidant Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Al-Imam Muhammad Ibn Saud Islamic University