Visualization of <scp>OPN</scp> ‐Targeted Self‐Assembled Micelles Encapsulated With an <scp>SIRT6</scp> Activator and Doped Indocyanine Green for Attenuating Vascular Aging
The visualized OPN-targeted micelles encapsulating MDL800 and ICG effectively attenuate vascular aging in a naturally aging mouse model. This delivery system holds promise as a therapeutic strategy for delaying vascular aging in the future.
Authors
- Yi Hou (ORCID: https://orcid.org/0000-0001-7026-6929)
- Zhiyi Fang (ORCID: https://orcid.org/0000-0002-6627-5387)
- Cheng Xue Qin (ORCID: https://orcid.org/0000-0003-2169-2686)
- Ning‐Yi Sun
- Sulei Li
- Tingting Lu (ORCID: https://orcid.org/0000-0002-1773-9878)
- Mengqi Xu (ORCID: https://orcid.org/0000-0001-8264-7083)
- Linghuan Wang
- Yan Fang (ORCID: https://orcid.org/0000-0001-7858-2539)
- Renzheng Chen (ORCID: https://orcid.org/0009-0009-2241-2077)
- Wenyue Li (ORCID: https://orcid.org/0000-0003-0063-9624)
- Jing Liu (ORCID: https://orcid.org/0000-0002-1019-0843)
- Hui Li (ORCID: https://orcid.org/0000-0003-0551-9912)
- Feng Cao (ORCID: https://orcid.org/0000-0002-1010-6429)
- Lei Tian (ORCID: https://orcid.org/0000-0002-7216-5352)
- Xiaojing Wan
- Xiaoying Shen (ORCID: https://orcid.org/0000-0002-0618-0423)
- Yan Ma (ORCID: https://orcid.org/0009-0008-0887-1261)
Institutions
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
- Beijing University of Chemical Technology (CN)
Publication Details
- Journal
- Aging Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/agm2.70045
- Primary Topic
- Porphyrin and Phthalocyanine Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00