Anodal M1 tDCS shapes frequency-specific functional connectivity and network topology in Parkinson's disease
Therapeutic effects of anodal M1-tDCS appear to be mediated by frequency-specific modulation of cortical networks, enhancing α-band synchronization and reducing β-band hypersynchrony, alongside a topological reconfiguration of brain architecture. These network-level effects strengthen the rationale for using tDCS in PD, particularly as a potential therapeutic option in the intermediate stage.
Authors
- Matteo Conti (ORCID: https://orcid.org/0000-0003-2879-2209)
- Francesca Di Giuliano (ORCID: https://orcid.org/0000-0002-6067-183X)
- Davide Mascioli (ORCID: https://orcid.org/0009-0009-0292-1640)
- Clara Simonetta (ORCID: https://orcid.org/0009-0007-3269-8684)
- Mariangela Pierantozzi (ORCID: https://orcid.org/0000-0002-4507-4666)
- Tommaso Schirinzi (ORCID: https://orcid.org/0000-0002-2517-6278)
- Jacopo Bissacco (ORCID: https://orcid.org/0009-0003-2350-4121)
- Valerio Ferrari
- Chiara Salimei (ORCID: https://orcid.org/0000-0002-1649-0417)
- Alessandro Stefani (ORCID: https://orcid.org/0000-0002-1806-8922)
- Nicola Biagio Mercuri (ORCID: https://orcid.org/0000-0001-6700-7491)
- Maria Mancini
- Federico Carparelli
- Veronica Buttarazzi (ORCID: https://orcid.org/0009-0002-6470-6160)
- Silvio Bagetta
Institutions
- University of Rome Tor Vergata (IT)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-10-26
- DOI
- https://doi.org/10.1016/j.brs.2025.10.016
- Citations
- 1
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39