Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signaling

BPG and BWG remarkably ameliorated I/R-induced AKI through modulation of Nrf2/HO-1/NF-κB/Caspase-3 signaling pathway, with BWG exhibiting more substantial renoprotective effects.

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Publication Details

Journal
Journal of Ginseng Research
Published
2025-10-26
DOI
https://doi.org/10.1016/j.jgr.2025.10.007
Primary Topic
Ginseng Biological Effects and Applications
Type
article
Field-Weighted Citation Impact
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article

Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signaling

Byung‐Yong Park, Md Shiblee Sadik Sabuj, Ryunhee Kim, Dongchoon Ahn et al.
Journal of Ginseng Research
Ginseng Biological Effects and Applications
article

Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signaling

Byung‐Yong Park, Md Shiblee Sadik Sabuj, Ryunhee Kim, Dongchoon Ahn, Hyun‐Jin Tae, Md Rashedunnabi Akanda, Ye Ji Kim, Hyo‐Jin Ro, Joonseok Lee, Seung Hyun Lee, J.-M. Oh, In‐Shik Kim, Myung-Kon Kim
article en

Abstract

BPG and BWG remarkably ameliorated I/R-induced AKI through modulation of Nrf2/HO-1/NF-κB/Caspase-3 signaling pathway, with BWG exhibiting more substantial renoprotective effects.

Journal of Ginseng ResearchVol. 50(1)
Sylhet Agricultural University (BD), National Institute of Animal Science (KR), Jeonbuk National University (KR)
Openalex Percentile: Top 73%
Ginseng Biological Effects and Applications
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