Extracellular vesicle and particle-based blood test for ovarian cancer screening of average risk population: a promising nested case control study using preclinical samples
The EVP-based blood test exhibits high sensitivity and specificity in detecting HGSC in preclinical samples, supporting its further evaluation as a potential annual screening tool for OC in average-risk women.
Authors
- Dawn Mattoon (ORCID: https://orcid.org/0009-0001-4198-5614)
- Sanchari Banerjee (ORCID: https://orcid.org/0000-0003-2511-0604)
- Laura Bortolin
- Anthony D. Couvillon (ORCID: https://orcid.org/0000-0002-0969-7364)
- Michael Smith (ORCID: https://orcid.org/0000-0003-2060-172X)
- Delaney M. Byrne (ORCID: https://orcid.org/0000-0003-3752-9648)
- Steven J. Skates
- Troy Hawkins (ORCID: https://orcid.org/0000-0002-6982-5014)
- Daniel P. Salem (ORCID: https://orcid.org/0000-0001-6345-6388)
- MacKenzie S. King
- Aleksandra Gentry‐Maharaj (ORCID: https://orcid.org/0000-0001-7270-9762)
- Emily S. Winn-Deen (ORCID: https://orcid.org/0000-0003-4146-3274)
- David F. Ransohoff (ORCID: https://orcid.org/0000-0002-2200-039X)
- Toumy Guettouche (ORCID: https://orcid.org/0009-0005-7342-3279)
- Brendan D. Manning (ORCID: https://orcid.org/0000-0003-3895-5956)
- Usha Menon (ORCID: https://orcid.org/0000-0003-3708-1732)
- Sophia Apostolidou (ORCID: https://orcid.org/0000-0003-2659-0451)
- Timothy Santos-Heiman (ORCID: https://orcid.org/0009-0003-5059-4986)
- Christine D. Berg
- Brittany Grimes
Institutions
- University of North Carolina at Chapel Hill (US)
Publication Details
- Journal
- Gynecologic Oncology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.ygyno.2025.10.003
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81