Yinchenhao decoction and its active compound rhein ameliorate intrahepatic cholestasis of pregnancy in mice via modulation of intestinal flora
YCHD and rhein could have beneficial impacts on ICP mouse models through the modulation of gut microbiota, offering a novel approach to clinical ICP management.
Authors
- Shuaijun Ren
- Yuping Zhou (ORCID: https://orcid.org/0000-0003-0693-4747)
- Jiating Feng
- Jia‐Yi Wang (ORCID: https://orcid.org/0000-0002-9106-3351)
- Rongrong Xuan
- Yajie Gao (ORCID: https://orcid.org/0000-0002-0218-7134)
- Jialin Li (ORCID: https://orcid.org/0000-0001-9858-2632)
- Ting Xiang
Institutions
- Ningbo University (CN)
- Ningbo University Affiliated Hospital (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.phymed.2025.157397
- Citations
- 2
- Primary Topic
- Phytochemistry and biological activity of medicinal plants
- Type
- article
- Field-Weighted Citation Impact
- 3.50