Diagnostic Accuracy of Endometrial Sampling Methods for Determining Histologic Type and Grade in Endometrial Cancer: A Retrospective Cohort Study

Endometrial sampling is moderately accurate for determining histologic type and grade in endometrial cancer. Hysteroscopy offers the highest precision for preoperative diagnosis, particularly in assessing histologic type and grade, supporting its role as the preferred diagnostic method. Future studies integrating molecular markers with histologic evaluation hold promise for improving diagnostic accuracy and optimizing treatment outcomes.