Complete genome and comparative genomic analysis of cefpodoxime resistant Pantoea septica strain GABEPS69 isolated from saliva of a patient diagnosed with treatment resistant schizophrenia
This study presents a first complete genome of P. septica, revealing its genomic architecture, resistance, and virulence potential. Detailed plasmid analysis and comparative genomics enhance our understanding of the species clinical relevance and microbiome-modulating capacity. These findings motivate surveillance of transient oral microbiota in at-risk populations, including patients receiving clozapine.
Authors
- Elaine Murray (ORCID: https://orcid.org/0000-0003-0170-6809)
- Aneesa Mangalam Lonappan
- Brian P. Hallahan (ORCID: https://orcid.org/0000-0003-0518-9757)
- Francesca McDonagh (ORCID: https://orcid.org/0000-0002-0830-4899)
- Kasthuri J. Venkateswaran (ORCID: https://orcid.org/0000-0002-6742-0873)
- Georgios Miliotis (ORCID: https://orcid.org/0000-0002-0944-2206)
- Aneta Kovářová (ORCID: https://orcid.org/0009-0008-4812-1553)
- Niamh McEvoy
- Andy O’Connor
- Anna Tumeo (ORCID: https://orcid.org/0009-0007-7689-2809)
Institutions
- Jet Propulsion Laboratory (US)
- University of Ulster (GB)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Altnagelvin Area Hospital (GB)
Publication Details
- Journal
- International Journal of Medical Microbiology
- Published
- 2025-10-26
- DOI
- https://doi.org/10.1016/j.ijmm.2025.151681
- Primary Topic
- Plant Pathogenic Bacteria Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Galway