Thyroid antibody status, thyroid function, and the risk of coronary heart disease and stroke: an individual participant data analysis from 14 cohorts
Positive TPOAb status was not associated with increased risk of CHD or stroke. These findings do not support the use of TPOAb testing for cardiovascular risk assessment in the overall population or among individuals with subclinical hypothyroidism.
Authors
- Suzanne J. Brown (ORCID: https://orcid.org/0000-0002-8413-561X)
- Henry Völzke (ORCID: https://orcid.org/0000-0001-7003-399X)
- Jacobijn Gussekloo (ORCID: https://orcid.org/0000-0001-7186-8278)
- Isabela M. Benseñor (ORCID: https://orcid.org/0000-0002-6723-5678)
- Nicolas Rodondi (ORCID: https://orcid.org/0000-0001-9083-6896)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Robin P. F. Dullaart (ORCID: https://orcid.org/0000-0002-3844-5254)
- José Augusto Sgarbi (ORCID: https://orcid.org/0000-0001-7187-984X)
- Heba Alwan (ORCID: https://orcid.org/0000-0001-5516-6022)
- Frank J. Wolters (ORCID: https://orcid.org/0000-0003-2226-4050)
- Fereidoun Azizi
- Massimo Iacoviello (ORCID: https://orcid.org/0000-0001-9613-5062)
- Anne Rentoumis Cappola (ORCID: https://orcid.org/0000-0002-0883-9754)
- Layal Chaker (ORCID: https://orcid.org/0000-0001-7855-5418)
- Sergio Valdés (ORCID: https://orcid.org/0000-0001-8623-4331)
- Tinh‐Hai Collet (ORCID: https://orcid.org/0000-0002-3243-1222)
- Cinzia Del Giovane (ORCID: https://orcid.org/0000-0002-5028-932X)
- Orestis Efthimiou (ORCID: https://orcid.org/0000-0002-0955-7572)
- Maryam Kavousi (ORCID: https://orcid.org/0000-0001-5976-6519)
- Bjørn Olav Åsvold (ORCID: https://orcid.org/0000-0003-3837-2101)
- Anna Köttgen (ORCID: https://orcid.org/0000-0002-4671-3714)
- John P. Walsh (ORCID: https://orcid.org/0000-0002-1766-2612)
- Ola Hysaj (ORCID: https://orcid.org/0000-0002-5669-0210)
- Till Ittermann (ORCID: https://orcid.org/0000-0002-0154-7353)
- Stella Trompet (ORCID: https://orcid.org/0000-0001-5006-0528)
- Cristina Maldonado‐Araque (ORCID: https://orcid.org/0000-0002-3452-3489)
- Elizabeth Selvin (ORCID: https://orcid.org/0000-0002-3539-2070)
- Bruce M. Psaty
Institutions
- University of Foggia (IT)
- University of Geneva (CH)
- University of Bern (CH)
- University of Modena and Reggio Emilia (IT)
- Washington State Department of Health (US)
- Bern University of Applied Sciences (CH)
- University Medical Center Groningen (NL)
- Johns Hopkins University (US)
- Faculdade de Medicina de Marília (BR)
- University of Freiburg (DE)
- University of Groningen (NL)
- The University of Western Australia (AU)
- Norwegian University of Science and Technology (NO)
- Universitätsmedizin Greifswald (DE)
- Diabetes Australia (AU)
- Leiden University Medical Center (NL)
- University Hospital of Bern (CH)
- University Medical Center Freiburg (DE)
- Erasmus MC (NL)
- Sir Charles Gairdner Hospital (AU)
- St Olav's University Hospital (NO)
- Research Institute for Endocrine Sciences (IR)
- University Hospital of Geneva (CH)
- Department of Health (TW)
- Hospital Universitário da Universidade de São Paulo (BR)
- Instituto de Investigación Biomédica de Málaga (ES)
- Shahid Beheshti University of Medical Sciences (IR)
- Geneva College (US)
- University of Pennsylvania (US)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1093/ejendo/lvaf209
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Bern
- Inselspital, Universitätsspital Bern