One new benzoate glycoside from <i>Gentiana triflora</i> pall

<i>Gentiana triflora</i> Pall. has anti-inflammatory constituents. Chemical studies on the ethanol extract of <i>G. triflora</i> afforeded one previously unreported benzoate glycoside (<b>1</b>) and a known one 2-hydroxy-3-<i>O</i>-<i>β</i>-D-glucopyranosyl-benzoic acid (<b>2</b>) Anti-inflammatory bioassay showed that both compounds <b>1</b> and <b>2</b> displayed a weak anti-inflammatory effect (IC<sub>50</sub> value of 35.2 μM and 28.9 μM) in the RAW 264.7 macrophages.

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Publication Details

Journal
Natural Product Research
Published
2025-10-25
DOI
https://doi.org/10.1080/14786419.2025.2567639
Primary Topic
Phytochemistry and Biological Activities
Type
article
Field-Weighted Citation Impact
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article

One new benzoate glycoside from Gentiana triflora pall

S. N. Liu, Gang Chen, Ju Yang, Yun Sun
Natural Product Research
Phytochemistry and Biological Activities
article

One new benzoate glycoside from Gentiana triflora pall

S. N. Liu, Gang Chen, Ju Yang, Yun Sun
article en

Abstract

<i>Gentiana triflora</i> Pall. has anti-inflammatory constituents. Chemical studies on the ethanol extract of <i>G. triflora</i> afforeded one previously unreported benzoate glycoside (<b>1</b>) and a known one 2-hydroxy-3-<i>O</i>-<i>β</i>-D-glucopyranosyl-benzoic acid (<b>2</b>) Anti-inflammatory bioassay showed that both compounds <b>1</b> and <b>2</b> displayed a weak anti-inflammatory effect (IC<sub>50</sub> value of 35.2 μM and 28.9 μM) in the RAW 264.7 macrophages.

Natural Product Research
Shenyang Pharmaceutical University (CN), Northeastern University (US), Xinjiang Medical University (CN), Orthopaedic Hospital (US), Shenyang 242 Hospital (CN)
Openalex Percentile: Top 77%
Phytochemistry and Biological Activities
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