In Silico Comparison of Photon Versus Proton Based Stereotactic Body Radiotherapy With Increasing Maximum Peak Dose for Treatment of Primary Renal Cell Carcinoma
PT-SBRT improved target coverage while reducing dose to the involved kidney and adjacent OARs. Protons allow delivery of maximum peak dose escalated plans without exceeding the normal tissues limit and have the potential to better preserve renal function. Prospective studies are warranted to validate these findings and potential clinical benefits.
Authors
- Anh Tran (ORCID: https://orcid.org/0009-0005-7853-9342)
- Stephen Greco (ORCID: https://orcid.org/0000-0003-3667-1044)
- Aditya Halthore
- Michael J. Goldstein (ORCID: https://orcid.org/0000-0001-5233-2814)
- Daniel Y. Song (ORCID: https://orcid.org/0000-0002-3495-8677)
- Curtiland Deville (ORCID: https://orcid.org/0000-0003-4846-6486)
- Heng Li (ORCID: https://orcid.org/0000-0002-6666-0277)
- Hao Chen (ORCID: https://orcid.org/0000-0002-6282-0237)
- Rachit Kumar (ORCID: https://orcid.org/0000-0003-4471-7145)
- S. Shaaban (ORCID: https://orcid.org/0000-0002-8443-5655)
Institutions
- Johns Hopkins University (US)
- University of South Florida (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- International Journal of Particle Therapy
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.ijpt.2025.101210
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00