Association of behavioral economic demand for kratom with DSM-5 use disorder: quantity and likelihood-based demand approaches
This study is the first to demonstrate that purchase tasks can quantify the reinforcing efficacy of kratom and emphasizes the temporal specificity of the association between purchase tasks and problem behaviors. These findings also suggest that demand indices from Quantity- and Likelihood-based tasks differentially relate to KUD, emphasizing the importance of task and outcome selection.
Authors
- Justin Strickland (ORCID: https://orcid.org/0000-0002-0669-5507)
- David H. Epstein (ORCID: https://orcid.org/0000-0001-8147-0386)
- Derek D. Reed (ORCID: https://orcid.org/0000-0002-5854-3425)
- Kirsten E. Smith (ORCID: https://orcid.org/0000-0002-9278-1830)
- Zachary Pierce-Messick (ORCID: https://orcid.org/0000-0001-6765-0671)
- Samuel F. Acuff (ORCID: https://orcid.org/0000-0002-1934-2639)
Institutions
- National Institute on Drug Abuse (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Massachusetts General Hospital (US)
- Institutes for Behavior Resources (US)
Publication Details
- Journal
- Addictive Behaviors Reports
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.abrep.2025.100638
- Primary Topic
- Alkaloids: synthesis and pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00