Rotator cuff repair and biologic augmentation—what do we know?

The field of biologic augmentation for RCR is rapidly evolving and has demonstrated substantial potential in improving structural integrity and healing rates. PRP, BMAC, as well as scaffold- or graft-based strategies, have all shown promise; however, variability in study methodology, preparation techniques, and clinical outcomes continue to limit definitive recommendations. Key challenges remain, including the need for optimization and standardization of biologic formulations, patient selection criteria, and cost-effective analyses. The need for well-powered, high-quality randomized controlled trials with standardized protocols are paramount to guiding clinical decision-making. The need to optimize RCR is clear, and the interest is evident in the numerous studies in the field. Future studies should aim to establish clear guidelines for biologic augmentation, ensuring that evidence-based applications can optimize patient outcomes in the future.