An in vivo model for transcranial direct current stimulation of the motor cortex in awake mice
The current study demonstrates the feasibility of a mouse model of M1-tDCS to accomplish similar modulatory effects of tDCS on cortical excitability as observed in human experiments. A proper adjustment of tDCS parameters, as compared to application in humans, is however required to obtain these translational effects since a higher density current was necessary in this study to obtain effects comparable to those achieved in humans.
Authors
- Pablo Alejandro Reyes Velasquez (ORCID: https://orcid.org/0000-0002-8805-2731)
- Christoph van Thriel (ORCID: https://orcid.org/0000-0003-3215-9262)
- Carlos A. Sánchez-León (ORCID: https://orcid.org/0000-0002-5278-9758)
- Michael A. Nitsche (ORCID: https://orcid.org/0000-0002-2207-5965)
Institutions
- TU Dortmund University (DE)
- Leibniz Research Centre for Working Environment and Human Factors (DE)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.brs.2025.10.018
- Citations
- 1
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.84