Bone disease burden does not impact overall survival in newly diagnosed patients with multiple myeloma − a single center, retrospective imaging analysis on 119 patients
While VCFs identified on WBLDCT correlate with poor outcomes in univariate analysis, they do not serve as independent prognostic markers when adjusting for established clinical factors. These findings suggest that in the era of novel anti-myeloma therapeutics, the bone disease burden at diagnosis may not impact prognosis significantly.
Authors
- Vasiliki Spiliopoulou (ORCID: https://orcid.org/0009-0009-5016-8729)
- Efstathios Kastritis (ORCID: https://orcid.org/0000-0001-8191-5832)
- Evangelos Eleutherakis‐Papaiakovou (ORCID: https://orcid.org/0000-0003-3407-5994)
- Vassilis Koutoulidis (ORCID: https://orcid.org/0000-0001-6281-8586)
- Lia A. Moulopoulos (ORCID: https://orcid.org/0000-0001-6009-1088)
- Evangelos Terpos (ORCID: https://orcid.org/0000-0001-5133-1422)
- Stylianos Mavropoulos-Papoudas
- Nikolaos Kanellias
- Panagiotis Malandrakis (ORCID: https://orcid.org/0000-0002-4673-171X)
- Foteini Theodorakakou (ORCID: https://orcid.org/0000-0001-6926-0351)
- Maria Douka
- Magdalini Migkou
- Maria Gavriatopoulou (ORCID: https://orcid.org/0000-0002-6244-1229)
- Despina Fotiou (ORCID: https://orcid.org/0000-0002-0618-8900)
- Ioannis Ntanasis-Stathopoulos
- Meletios A. Dimopoulos
Institutions
- Korea University (KR)
- National and Kapodistrian University of Athens (GR)
Publication Details
- Journal
- Journal of bone oncology
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.jbo.2025.100720
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00