The ceRNA network of LINC00536/miR-204-5p/TGFBR2: A novel therapeutic target for breast cancer diagnosis and treatment
LINC00536 promotes BC progression and activates TGF-β signaling via miR-204-5p/TGFBR2, with its expression correlating with features of the TME, establishing its potential as a diagnostic/prognostic biomarker and therapeutic target.
Authors
- Yong Bai (ORCID: https://orcid.org/0000-0002-0863-226X)
- Linjie Lei
- Dilare Lidifu
- Shumei Feng (ORCID: https://orcid.org/0000-0003-1614-6373)
- Jing Chen (ORCID: https://orcid.org/0000-0001-5972-3623)
- Xin Zhao (ORCID: https://orcid.org/0000-0002-1276-5858)
- Yan Chen (ORCID: https://orcid.org/0000-0003-3808-1259)
- Munire Shataer
- Liangying Ma
- Tayier Tuersong
Institutions
- Xinjiang Medical University (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Cellular Signalling
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.cellsig.2025.112192
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00