Ferroptosis-Related Gene CRYAB in Asthma: Bioinformatics Identification and Experimental Validation
This study is the first to highlight the pivotal role of CRYAB among FRGs in asthma pathogenesis. Notably, overexpression of CRYAB inhibits ferroptosis-suggesting its potential as a valuable biomarker for personalized diagnosis and therapy for asthma.
Authors
- He Zhu (ORCID: https://orcid.org/0000-0002-3828-3312)
- Fan Gao (ORCID: https://orcid.org/0009-0009-9190-0613)
- Limin Zhao (ORCID: https://orcid.org/0009-0006-5159-8745)
- Yingjie Guo (ORCID: https://orcid.org/0000-0003-3007-9584)
- Jiahui Lei (ORCID: https://orcid.org/0000-0002-7032-2916)
- Jinxin Ma (ORCID: https://orcid.org/0000-0002-0478-7766)
Institutions
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jir.s547828
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00