Cat-Scratch Disease Presenting as Isolated Neuroretinitis (Bartonella henselae): A Case Report

Cat-scratch disease (CSD), a rare infectious disorder typically presenting with systemic manifestations such as fever and lymphadenopathy, uncommonly involves ocular structures, with neuroretinitis being one of its more frequent ocular manifestations. We report an unusual case of CSD presenting as isolated neuroretinitis in the absence of constitutional symptoms. The patient is an 18-year-old female who presented with decreased vision in her left eye and the appearance of shadows. She reported no systemic symptoms such as fever or swollen lymph nodes. Fundus examination revealed optic disc edema, retinal edema in the posterior pole, and macular star exudates. Diagnosis was confirmed by a history of cat exposure and positive serology for <i>Bartonella henselae</i> antibodies. Treatment with oral doxycycline, combined with azithromycin and low-dose glucocorticoids, resulted in significant visual improvement. This case highlights that CSD should be considered in cases of unexplained neuroretinitis, and a careful history regarding cat contact is essential to avoid misdiagnosis.

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Publication Details

Journal
Cureus
Published
2025-10-25
DOI
https://doi.org/10.7759/cureus.95383
Primary Topic
Bartonella species infections research
Type
article
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article

Cat-Scratch Disease Presenting as Isolated Neuroretinitis (Bartonella henselae): A Case Report

Ke Wu, Xing Jian-wei, Yong Wang
Cureus
Bartonella species infections research
article

Cat-Scratch Disease Presenting as Isolated Neuroretinitis (Bartonella henselae): A Case Report

Ke Wu, Xing Jian-wei, Yong Wang
article en

Abstract

Cat-scratch disease (CSD), a rare infectious disorder typically presenting with systemic manifestations such as fever and lymphadenopathy, uncommonly involves ocular structures, with neuroretinitis being one of its more frequent ocular manifestations. We report an unusual case of CSD presenting as isolated neuroretinitis in the absence of constitutional symptoms. The patient is an 18-year-old female who presented with decreased vision in her left eye and the appearance of shadows. She reported no systemic symptoms such as fever or swollen lymph nodes. Fundus examination revealed optic disc edema, retinal edema in the posterior pole, and macular star exudates. Diagnosis was confirmed by a history of cat exposure and positive serology for <i>Bartonella henselae</i> antibodies. Treatment with oral doxycycline, combined with azithromycin and low-dose glucocorticoids, resulted in significant visual improvement. This case highlights that CSD should be considered in cases of unexplained neuroretinitis, and a careful history regarding cat contact is essential to avoid misdiagnosis.

CureusVol. 17(10)
Shaanxi Provincial People's Hospital (CN)
Openalex Percentile: Top 68%
Bartonella species infections research
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Cat-Scratch Disease Presenting as Isolated Neuroretinitis (Bartonella henselae): A Case Report — Ke Wu, Xing Jian-wei, et al. · Cureus (2025) | TGRS Research Map | TGRS