Mediation and prognostic value of apparent diffusion coefficient in HCC patients receiving immune checkpoint inhibitors
The sADC could indirectly reflect tumor microenvironment characteristics. The association between tumor burden and inflammatory markers was observed regarding sADC. Baseline sADC and its change predict prognosis in ICI-treated HCC patients.
Authors
- Shanshan Jiang (ORCID: https://orcid.org/0000-0003-3461-6076)
- Yanjie Yang (ORCID: https://orcid.org/0000-0002-8638-5313)
- Xiaona Fu
- Sichen Wang (ORCID: https://orcid.org/0009-0002-8492-3234)
- Jie Lou (ORCID: https://orcid.org/0009-0006-6064-1450)
- Peng Sun (ORCID: https://orcid.org/0000-0002-0095-4782)
- Yixing Li (ORCID: https://orcid.org/0000-0002-8190-9931)
- Lian Yang (ORCID: https://orcid.org/0000-0003-4664-2474)
- Lixia Wang (ORCID: https://orcid.org/0000-0003-3591-4315)
- Yusheng Guo (ORCID: https://orcid.org/0000-0003-2977-9356)
- Bingxin Gong
- Lianwei Miao
Institutions
- Union Hospital (HK)
- Harbin Institute of Technology (CN)
- Philips (China) (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Precision for Medicine (United States) (US)
- State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing (CN)
- Wuhan Union Hospital (CN)
- Hubei University of Education (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Hubei University (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1186/s13244-025-02115-1
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Science and Technology Major Project
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities