Real-life impact of anti-IL5 therapy on exacerbation types in patients with obstructive lung disease
In this nationwide cohort study, treatment targeting eosinophilic inflammation was significantly associated with reduced moderate and severe exacerbations, with seemingly less impact on corticosteroid-treated exacerbations in (current smoking) patients with coexisting COPD, but still a large number of hospitalisations were prevented.
Authors
- Lowie E.G.W. Vanfleteren (ORCID: https://orcid.org/0000-0002-4387-4096)
- Delphine Vauterin (ORCID: https://orcid.org/0000-0002-8932-476X)
- Lies Lahousse (ORCID: https://orcid.org/0000-0002-3494-4363)
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- University of Gothenburg (SE)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/bmjresp-2025-003413
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Australian Government
- Universiteit Gent