Does the frailty index applied to randomised controlled trials really measure frailty?
In many cardiovascular RCTs, frailty indices focus on cardiometabolic deficits rather than measures of function. These frailty indices need to be validated against outcomes important to people living with frailty before being used to inform treatment. Until then, we would emphasise caution.
Authors
- Jim Lewsey (ORCID: https://orcid.org/0000-0002-3811-8165)
- David McAllister (ORCID: https://orcid.org/0000-0003-3550-1764)
- Peter Hanlon (ORCID: https://orcid.org/0000-0002-5828-3934)
- Heather Wightman
- Rîme Bousetta
Institutions
- Université Libre de Bruxelles (BE)
- University of Glasgow (GB)
Publication Details
- Journal
- Age and Ageing
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1093/ageing/afaf314
- Citations
- 4
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 4.90