Association Between Autoimmune Diseases, Treatments, and Dementia Risk: A Population-Based Case-Control Study From Taiwan.
<b>Conclusions:</b> Certain autoimmune diseases are significantly associated with an increased risk of dementia, particularly vascular dementia, highlighting the distinct role of inflammation. Effective prevention or treatment of autoimmune diseases may reduce dementia incidence by 0.8%. While immunosuppressants show potential for risk reduction, further prospective studies are needed to confirm this effect.
Authors
- Shi‐Heng Wang (ORCID: https://orcid.org/0000-0002-8466-2698)
- Wei‐Lieh Huang (ORCID: https://orcid.org/0000-0001-5786-3366)
- Ming‐Shiang Wu (ORCID: https://orcid.org/0000-0002-1940-6428)
- Chi‐Shin Wu (ORCID: https://orcid.org/0000-0003-2762-7295)
- Sheng-Han Cheng
- Kuo‐Shu Chen (ORCID: https://orcid.org/0000-0001-7574-415X)
- Ying-Ming Chiu
Institutions
- National Chung Hsing University (TW)
- National Taiwan University (TW)
- China Medical University (TW)
- China Medical University Hospital (TW)
- National Taiwan University Hospital (TW)
- Tungs' Taichung MetroHarbor Hospital (TW)
- Kang-Ning Junior College of Medical Care and Management (TW)
- National Yunlin University of Science and Technology (TW)
Publication Details
- Journal
- PubMed
- Published
- 2025-10-15
- DOI
- https://doi.org/10.4088/jcp.25m15774
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00