Inflammatory and Nutrition‐Glucose Metabolic Factors in Relation to Sarcopenia Prevalence Among <scp>US</scp> Adults: Evidence From <scp>NHANES</scp> 2015–2018
Inflammatory markers (CRP, WBC) and metabolic indicator (HbA1c) synergistically drive sarcopenia pathogenesis. CRP-HbA1c has superior predictive value. Higher levels of vitamin D play a significant protective role against sarcopenia. Nonlinear analysis confirms dose-dependent positive correlations for CRP and WBC (p-nonlinear < 0.05). These findings emphasize that chronic inflammation and poor blood glucose control are key mechanisms in the development of sarcopenia.
Authors
- Jianming Wei (ORCID: https://orcid.org/0000-0002-1574-2109)
- Wenjun Jiao (ORCID: https://orcid.org/0000-0001-5458-0440)
- Xuedong Jia (ORCID: https://orcid.org/0000-0003-4317-5284)
- Tao Feng (ORCID: https://orcid.org/0000-0002-4498-5118)
- Yanyan Jiang (ORCID: https://orcid.org/0000-0002-5268-9896)
- Sufang Chen
- Dong Wang (ORCID: https://orcid.org/0000-0001-7877-7440)
- Jiajia Wang
- Cong Wu (ORCID: https://orcid.org/0009-0008-9901-1741)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1111/ggi.70222
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16