Using neuropsychological test scores to predict beta-amyloid deposition in older adults across the late-life cognitive continuum
Cognitive test scores significantly predicted aβ deposition, with memory measures in particular accounting for approximately a third of the variance. These results provide a proof of concept for use of neuropsychological test scores as tools for estimating biomarkers in neurodegenerative disease.
Authors
- Jasmin E. Guevara (ORCID: https://orcid.org/0000-0002-3621-8306)
- Allie R. Geiger (ORCID: https://orcid.org/0009-0006-3428-7013)
- John M. Hoffman (ORCID: https://orcid.org/0000-0001-8799-8069)
- Kevin M. Duff (ORCID: https://orcid.org/0000-0002-9336-2400)
- Jace B. King (ORCID: https://orcid.org/0000-0002-0206-0475)
Institutions
- Oregon Health & Science University (US)
- University of Utah (US)
- Huntsman Cancer Institute (US)
Publication Details
- Journal
- Journal of Clinical and Experimental Neuropsychology
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1080/13803395.2025.2578345
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00