Parametric description, analysis, and optimization of the connector shape in balloon-expandable stents

Stents are widely used in interventional therapies to treat vascular stenosis and other obstructions. Their geometry and connector morphology critically influence mechanical properties (radial stiffness, bending compliance, fatigue resistance) and therapeutic performance. This study introduces a parametric-optimization framework for stent continuous connectors. An efficient model via quintic polynomial splines models complex connectors with fewer control points; a data-driven method (Kriging + EI criterion) finds designs meeting target mechanical performance. Optimal designs maximizing key stiffness/compliance metrics are analyzed. This strategy extends to full stent design, offering a novel approach for vascular stent parametric design and fabrication.

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Publication Details

Journal
Computer Methods in Biomechanics & Biomedical Engineering
Published
2025-10-25
DOI
https://doi.org/10.1080/10255842.2025.2571194
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

Parametric description, analysis, and optimization of the connector shape in balloon-expandable stents

Menglei Yu, Zhigang Feng, Xiaoming Wang, Haibin Huang
Computer Methods in Biomechanics & Biomedical Engineering
Coronary Interventions and Diagnostics
article

Parametric description, analysis, and optimization of the connector shape in balloon-expandable stents

Menglei Yu, Zhigang Feng, Xiaoming Wang, Haibin Huang
article en

Abstract

Stents are widely used in interventional therapies to treat vascular stenosis and other obstructions. Their geometry and connector morphology critically influence mechanical properties (radial stiffness, bending compliance, fatigue resistance) and therapeutic performance. This study introduces a parametric-optimization framework for stent continuous connectors. An efficient model via quintic polynomial splines models complex connectors with fewer control points; a data-driven method (Kriging + EI criterion) finds designs meeting target mechanical performance. Optimal designs maximizing key stiffness/compliance metrics are analyzed. This strategy extends to full stent design, offering a novel approach for vascular stent parametric design and fabrication.

Computer Methods in Biomechanics & Biomedical Engineering
Sun Yat-sen University (CN), Guangzhou University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Openalex Percentile: Top 52%
Coronary Interventions and Diagnostics
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