Real-world data on treatment persistence and measures to minimize cardiovascular risk in rheumatic patients using upadacitinib

In real-world clinical settings, UPA persistence is lower among RA patients who have received prior IL-6i treatment. Treatment strategies to avoid UPA in patients with CVR appear to be primarily driven by pivotal safety studies rather than regulatory guidance.

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Publication Details

Journal
Lara D. Veeken
Published
2025-10-21
DOI
https://doi.org/10.1093/rheumatology/keaf547
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Real-world data on treatment persistence and measures to minimize cardiovascular risk in rheumatic patients using upadacitinib

Carlos Rodríguez Lozano, Alicia García-Dorta, Vanesa Hernández-Hernández, Federico Díaz‐González et al.
Lara D. Veeken
Rheumatoid Arthritis Research and Therapies
article

Real-world data on treatment persistence and measures to minimize cardiovascular risk in rheumatic patients using upadacitinib

Carlos Rodríguez Lozano, Alicia García-Dorta, Vanesa Hernández-Hernández, Federico Díaz‐González, Enrique González‐Dávila, Cristina Martínez González, Andrea Hernández-Martín, Cristina Rodríguez-Regalado, Elena Naveda-González, Sonia Peña-Montelongo
article en

Abstract

In real-world clinical settings, UPA persistence is lower among RA patients who have received prior IL-6i treatment. Treatment strategies to avoid UPA in patients with CVR appear to be primarily driven by pivotal safety studies rather than regulatory guidance.

Lara D. VeekenVol. 65(1)
Universidad de La Laguna (ES), Hospital Universitario de Canarias (ES), Hospital Universitario Nuestra Señora de Candelaria (ES), Hospital Universitario de Gran Canaria Doctor Negrín (ES), Hospital Universitario Virgen de las Nieves (ES)
Openalex Percentile: Top 56%
Rheumatoid Arthritis Research and Therapies
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