Glymphatic Function in Prodromal Parkinson's Disease: Associations With Symptoms, Gray Matter Volume, and Phenoconversion Risk
Reduced DTI-ALPS index in pPD-which may reflect altered glymphatic function-is associated with accelerated phenoconversion and correlates with clinical symptoms and cortico-thalamic structural changes.
Authors
- Yoon Seong Choi (ORCID: https://orcid.org/0000-0002-6034-9912)
- Jinyu Wen (ORCID: https://orcid.org/0000-0001-9312-8289)
- Amei Chen (ORCID: https://orcid.org/0000-0002-2074-6470)
- Xinhua Wei (ORCID: https://orcid.org/0000-0003-1074-4612)
- Junxiang Huang (ORCID: https://orcid.org/0000-0002-9743-0466)
- Peng Wu (ORCID: https://orcid.org/0000-0003-0564-0325)
- Yongzhou Xu
- Pek‐Lan Khong (ORCID: https://orcid.org/0000-0002-9280-6778)
- Zhanyu Kuang
Institutions
- National University of Singapore (SG)
- Guangzhou University (CN)
- Philips (China) (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Women and Children Medical Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1111/ene.70389
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Traditional Chinese Medicine Bureau of Guangdong Province
- Guangzhou Municipal Science and Technology Project